Comprehensive analysis of mouse retinal mononuclear phagocytes
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چکیده
منابع مشابه
Interferon‐beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization
Age-related macular degeneration (AMD) is a leading cause of vision loss among the elderly. AMD pathogenesis involves chronic activation of the innate immune system including complement factors and microglia/macrophage reactivity in the retina. Here, we show that lack of interferon-β signaling in the retina accelerates mononuclear phagocyte reactivity and promotes choroidal neovascularization (...
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ژورنال
عنوان ژورنال: Nature Protocols
سال: 2017
ISSN: 1754-2189,1750-2799
DOI: 10.1038/nprot.2017.032